ABC转运蛋白在真菌的致病性方面起着重要的作用。本研究查找和分析了稻瘟病菌基因组中47个ABC转运蛋白基因的外显子区、内含子区、5′-UTR和3′-UTR区中的SSR，并对编码区中SSR的扩张或收缩对蛋白结构的影响进行了预测。结果表明，SSR在这些基因的调控区和编码区分布不均一，且在基因的外显子区、内含子区、5′-UTR和3′-UTR区中SSR的组成和分布均不相同；基因的编码区中三碱基和六碱基SSR相对较多，SSR的基序大都表现为GC含量较高，编码的亲水性氨基酸出现频率远远高于疏水性氨基酸。根据稻瘟病菌自然群体中SSR的变化幅度，预测了SSR的扩张或收缩对蛋白二级结构的影响，发现SSR的扩张或收缩都可能对蛋白的结构产生影响。暗示着SSR的变异在致病相关基因的变异中可能扮演着重要角色。

ABC transporters play an important role in pathogenicity of fungi. In this study, 47 ABC transporter genes were retrieved from the genome of Magnaporthe grisea. The component and distribution of simple sequence repeats (SSR) within the extron, intron, 5′-UTR and 3′-UTR regions of these genes were analyzed respectively. Furthermore, effects of SSR expansion and contraction on protein structure in the gene coding regions was predicted. The results showed that component and distribution of the SSRs in these regions were different and the SSRs also distributed unevenly in regulation and function regions of these genes. Compared with other regions, the tri-nucleotide and hexa-nucleotide appeared more frequently in coding region. In addition, the G+C component was more abundant and the frequency of hydrophilic amino acids was relatively higher than that of hydrophobic amino acids in the SSRs. Depending on the variation among field isolates of M.grisea, the expansion or contraction of amino acids encoding SSR sequence were potentially affected on protein secondary structure and gene function. These data implicated that the mutation of SSR might play an important role in variation of pathogenicity-related genes.